Journal article
N. Weiss, G. Zamponi
ACS chemical neuroscience, 2019
ACS chemical neuroscience, 2019
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APA
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Weiss, N., & Zamponi, G. (2019). T-Type Channel Druggability at a Crossroads. ACS Chemical Neuroscience.
Chicago/Turabian
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Weiss, N., and G. Zamponi. “T-Type Channel Druggability at a Crossroads.” ACS chemical neuroscience (2019).
MLA
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Weiss, N., and G. Zamponi. “T-Type Channel Druggability at a Crossroads.” ACS Chemical Neuroscience, 2019.
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@article{n2019a,
title = {T-Type Channel Druggability at a Crossroads.},
year = {2019},
journal = {ACS chemical neuroscience},
author = {Weiss, N. and Zamponi, G.}
}
Abstract
Low-voltage activated T-type calcium channels mediate essential functions in the nervous system, and alteration of channel activity is causally linked to a number of neurological conditions. Therefore, T-type channels hold great promise as pharmacological targets for new medicines. In this Viewpoint, we discuss the potential of T-type channels as druggable targets and reevaluate the strategies available for developing therapeutically efficient and specific modulators of this channel.